Traffic entering Bedford from Bloomington and farther north from Indianapolis can use IN 37 southbound, while areas to the south near Paoli and Interstate 64 will use IN 37 northbound. From the east, US 50 westbound brings traffic from Seymour and Interstate 65. Areas to the west like Vincennes will follow US 50 eastbound. From the southeast, IN 60 at Mitchell brings traffic from Salem and Louisville.